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Leiter Prof. Christian Müller Spitalstrasse 2 CH-4056 Basel Schweiz

Kardiale autonome Funktion

Leiterin: Prof. Christine Meyer-Zürn Cardiovascular diseases (e.g. heart failure, acute and chronic coronary syndromes, valvular heart disease and cardiac arrhythmias such as atrial fibrillation) are associated with disturbances of the cardiac autonomic nervous system. Cardiac autonomic parameters can be used for diagnostic and therapeutic purposes and provide prognostic information. We investigate cardiac autonomic function primarily by the analysis of ECG signals. The main focus of our work is the analysis of cardiac autonomic function in patients with atrial fibrillation within the Swiss-AF studies. Our Team: Prof. Christine Meyer-Zürn, MD (Senior Scientist, Oberärztin) Dr. Peter Hämmerle, MD (Junior Scientist, Assistenzarzt) Vincent Schlageter, PhD (Biomedical Engineer) Prof. Michael Kühne, MD (Senior Advisor) Dr. Johannes Schier

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Selected publicationen: Hennings E, Coslovsky M, Paladini RE, Aeschbacher S, Knecht S, Schlageter V, Krisai P, Badertscher P, Sticherling C, Osswald S, Kühne M, Zuern CS, Swiss-AF Investigators. Assessment of the atrial fibrillation burden in Holter electrocardiogram recordings using artificial intelligence. Cardiovascular Digital Health Journal 2023; published online January 27. Hämmerle P, Aeschbacher S, Springer A, Eken C, Coslovsky M, Dutilh G, Moschovitis G, Rodondi N, Chocano P, Conen D, Osswald S, Kühne M, Zuern CS. Cardiac autonomic function and cognitive performance in patients with atrial fibrillation. Clin Res Cardiol. 2022 Jan;111(1):60-69. Hämmerle P, Eick C, Poli S, Blum S, Schlageter V, Bauer A, Rizas KD, Eken C, Coslovsky M, Aeschbacher S, Krisai P, Meyre P, Wuerfel J, Sinnecker T, Vesin JM, Beer JH, Moschovitis G, Bonati LH, Sticherling C, Conen D, Osswald S, Kühne M, Zuern CS. Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation. Front Cardiovasc Med. 2021 May 21;8:684461. Krisai P, Hämmerle P, Blum S, Meyre P, Aeschbacher S, Melchiorre-Mayer P, Baretella O, Rodondi N, Conen D, Osswald S, Kühne M, Zuern CS; Swiss-AF investigators. Prognostic significance of present atrial fibrillation on a single office electrocardiogram in patients with atrial fibrillation. J Intern Med. 2021 Mar;289(3):395-403. Hämmerle P, Eick C, Blum S, Schlageter V, Bauer A, Rizas KD, Eken C, Coslovsky M, Aeschbacher S, Krisai P, Meyre P, Vesin JM, Rodondi N, Moutzouri E, Beer J, Moschovitis G, Kobza R, Di Valentino M, Corino VDA, Laureanti R, Mainardi L, Bonati LH, Sticherling C, Conen D, Osswald S, Kühne M, Zuern CS; Swiss‐AF Study Investigators. Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation. J Am Heart Assoc. 2020 Aug 4;9(15):e016075.